Organic sulfuric acids and derivatives
Medchemexpress LLC Penbutolol sulfate ((-)-Terbuclomine) | 38363-32-5 | 98.89% | 5 MG
Penbutolol sulfate, also known as (-)-Terbuclomine, is a potent antagonist targeting both β-adrenoceptors and 5-HT receptors. It exhibits high affinity for these receptors, with reported Ki values of 11.6 nM for β-adrenoceptors and 11.9 nM for 5-HT receptors in specific rat and human brain regions. This compound is intended for research applications only.
- Potent β-adrenoceptor and 5-HT receptor antagonist.
- Ki values of 11.6 nM for β-adrenoceptors and 11.9 nM for 5-HT receptors.
- Inhibits 5-HT cell discharge in rat models.
- Enhances the effect of Paroxetine on elevating 5-HT levels in rat models.
Medchemexpress LLC Pregnanolone sulfate pyridinium | 124107-39-7 | 99.8% | 477.66 | C26H39NO5S | 100mg
Pregnanolone sulfate pyridinium is an endogenous neurosteroid that inhibits NMDA receptors and is neuroprotective[1]
Medchemexpress LLC Pregnanolone sulfate (pyridinium) | 124107-39-7 | 99.8% | 477.66 | C26H39NO5S | 50mg
Pregnanolone sulfate pyridinium is an endogenous neurosteroid that inhibits NMDA receptors and is neuroprotective[1]
Medchemexpress LLC Phenyl sulfate | 937-34-8 | 99.5% | 25 MG
Phenyl sulfate is an orally active gut microbiota-derived metabolite. It induces albuminuria and podocyte damage in experimental models of diabetes and can be used as a disease marker in diabetic kidney disease.
- Orally active gut microbiota-derived metabolite
- Induces albuminuria and podocyte damage in experimental models
- Used as a disease marker in diabetic kidney disease
Medchemexpress LLC Dopamine 4-sulfate | 38339-02-5 | 96.0% | 233.24 g/mol | C8H11NO5S | 5 MG
Dopamine 4-sulfate is a sulfated metabolite of the neurotransmitter dopamine used as a research reagent and metabolite reference for studies of dopamine metabolism and sulfotransferase activity. It is supplied as a high-purity solid for biochemical, analytical, and in vitro applications.
- Used as a metabolite reference in biochemical and pharmacological assays.
- Chemical formula C8H11NO5S; molecular weight 233.24 g/mol.
- Purity approximately 96% as supplied.
- Available in small research sizes: 1 mg, 5 mg, 10 mg, 50 mg.
- Suitable for analytical standards and in vitro studies.
Sigma Aldrich Fine Chemicals Biosciences Vincristine sulfate United50MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Medchemexpress LLC Sulfuric acid, mono(4-methylphenyl) ester | 3233-58-7 | 99.98% | 188.20 | 1 MG
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin that can cause renal damage and dysfunction. It shows antiproliferation activity, increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α, induces epithelial-mesenchymal transition (EMT), and activates the JNK and p38 MAPK signaling pathways. For research use only.
- Exhibits antiproliferation activity in a dose- and time-dependent manner
- Increases protein expression of HIF-1α and VHL
- Decreases protein expression of HIF-2α
- Induces epithelial-mesenchymal transition (EMT)
- Activates JNK and p38 MAPK signaling pathways
- Inhibits lipogenesis and increases lipolysis in adipocytes
- Induces osteoblast dysfunction
- Induces ROS production in primary osteoblastic cells
Medchemexpress LLC p-Cresyl sulfate potassium | 91978-69-7 | 99.95% | 226.29 | 50 MG
p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. It activates the JNK and p38 MAPK signaling pathways and has pro-inflammatory activity.
- Uremic toxin
- Binds to a prototype protein
- Activates JNK and p38 MAPK signaling pathways
- Has pro-inflammatory activity
Medchemexpress LLC Cefoselis (sulfate) | 122841-12-7 | 99.4% | 5 MG
Cefoselis sulfate, also known as FK-037, is a fourth-generation cephalosporin and a β-lactam antibiotic. It demonstrates good activity against a broad spectrum of Gram-positive and Gram-negative organisms and can penetrate the blood-brain barrier.
- Activity comparable to cefpirome and cefepime.
- Generally superior to ceftazidime.
- Highly effective against Hemophilus influenzae and Moraxella catarrhalis.
- Highly active against MSSA and MSCNS.
- Exhibits poor activity against MRSA, MRCNS, PRSP, and Enterococcus faecalis.
- No activity against Enterococcus faecium.
Medchemexpress LLC Vinblastine sulfate | 143-67-9 | 99.56% | 909.05 | 25 MG
Vinblastine sulfate is a cytotoxic alkaloid effective against various cancer types. It inhibits microtubule formation and suppresses nAChR with an IC50 of 8.9 μM. It blocks mitosis and induces apoptosis by altering p53 and causing DNA fragmentation, leading to an antiproliferative effect via Bax/Bcl-2 imbalance.
- Inhibits microtubule formation
- Suppresses nAChR activity
- Blocks mitosis and induces apoptosis
- Exhibits antiproliferative effects via Bax/Bcl-2 imbalance
- Modulates NFκB and JNK pathways
- Triggers apoptosis through mitochondrial pathway
- Targets Microtubule/Tubulin, Autophagy, and nAChR
- Involved in Cell Cycle/DNA Damage and Cytoskeleton pathways
- Soluble in water (50 mg/mL) and DMSO (≥ 44 mg/mL)
- Intended for research use only
Medchemexpress LLC Hydrazine sulfate 9 25g
Hydrazine sulfate is an orally active PEPCK inhibitor Hydrazine sulfate inhibits PEPCK and low-Km ALDH Hydrazine sulfate impairs gluconeogenesis and enhances the protective effect of energy substrates against MPP toxicity Hydrazine sulfate exacerbates liver damage in rats when combined with Ethanol Hydrazine sulfate can be used in the research of shock non-small cell lung cancer colorectal cancer and Parkinson s disease[1][2][3][4][5][6]
Medchemexpress LLC Dermatan sulphate sodium | 54328-33-5 | 50 MG
Dermatan sulphate sodium | 54328-33-5 | 50 MG