Organic sulfuric acids and derivatives
Medchemexpress LLC Dextran sulfate low 500mg | 9011-18-1 | 40,000 Da (average) | 500 MG
Dextran sulfate, low sulfate (average molecular weight ~40,000) is a sulfated polysaccharide used as a biochemical reagent. Common applications include reducing cell aggregation in culture, serving as a gel-forming agent in cosmetic formulations, and use in research probing complement/coagulation pathways and inflammatory or antiviral models.
- Average molecular weight around 40,000 (polydisperse polymer).
- Low-sulfate polyanion; soluble in aqueous media.
- Used to reduce cell aggregation in cell culture applications.
- Employs as a gel-forming or thickening agent in formulations.
- Analytical profile typically lists water content, total sulfur, pH, and low heavy metals.
Medchemexpress LLC Tasipimidine sulfate | 1465908-73-9 | 99.3% | 330.36 | 10 MG
Tasipimidine sulfate is an orally active and selective α2A-adrenoceptor agonist with a pEC50 of 7.57 for human α2A-adrenoceptors and an EC50 of 5.7 nM for rat α2-adrenoceptor. It can be used in research related to situational anxiety and fear.
- Orally active and selective α2A-adrenoceptor agonist.
- Reduces spontaneous locomotor activity in mice.
- Reduces the amplitude of the acoustic startle reflex in rats.
- Improves separation anxiety in dogs, leading to more positive owner ratings and significantly reduced destructive/rearranging behavior and vocalization at a dose of 30 μg/kg.
Medchemexpress LLC Framycetin sulfate | 4146-30-9 | 98.0% | 908.88 | 500 MG
Framycetin sulfate is an aminoglycoside antibiotic that acts as a potent inhibitor of RNase P cleavage activity. It competes for specific divalent metal ion binding sites in RNase P RNA and also inhibits hammerhead ribozyme. This compound is a 5″-azido neomycin B precursor and binds to the Drosha site in miR-525. It is used in the treatment of hepatic encephalopathy and infections caused by enteropathogenic E. coli.
- Potent RNase P cleavage activity inhibitor
- Inhibits hammerhead ribozyme
- Binds to the Drosha site in miR-525
- Effective against hepatic encephalopathy and enteropathogenic E. coli infections
Medchemexpress LLC Phenyl sulfate | 937-34-8 | 98% | 50 MG
Phenyl sulfate (Standard) is an orally active gut microbiota-derived metabolite, primarily used as an analytical standard for research and analytical applications. It has been identified as a disease marker in diabetic kidney disease, capable of inducing albuminuria and podocyte damage in experimental diabetes models. This analytical standard is suitable for use in qualitative, quantitative, and methodological research experiments, including techniques like HPLC, GC, and MS.
- Used as an analytical standard for research
- Suitable for HPLC, GC, and MS applications
- Functions as an orally active gut microbiota-derived metabolite
- Identified as a disease marker in diabetic kidney disease
Medchemexpress LLC p-Cresyl sulfate potassium | 91978-69-7 | 99.88% | 226.29 | 500 MG
p-Cresyl sulfate potassium | 91978-69-7 | 99.88% | 226.29 | 500 MG
Medchemexpress LLC Vinblastine sulfate | 143-67-9 | 99.6% | 909.05 | 100 MG
Vinblastine sulfate is a cytotoxic alkaloid effective against various cancer types. It inhibits microtubule formation and suppresses nAChR with an IC50 of 8.9 μM. This product is intended solely for research purposes.
- Inhibits microtubule formation and suppresses nAChR with an IC50 of 8.9 μM.
- Blocks mitosis in HeLa cells and induces apoptosis.
- Causes p53 alterations and DNA fragmentation, leading to apoptosis via Bax/Bcl-2 imbalance.
- Suppresses NFκB expression and its DNA binding activity.
- Triggers apoptosis through loss of mitochondrial membrane potential and activation of caspases.
- Demonstrates cytotoxicity across a broad range of human cell lines.
- Explored in various clinical trials for cancer treatment.
Medchemexpress LLC Momelotinib (sulfate) | 1056636-06-6 | 99.9% | 610.62 | 50 MG
Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, showing 10-fold selectivity versus JAK3 (IC50=155 nM). It inhibits the growth of Ba/F3-JAK2V617F and human erythroleukemia (HEL) cells (IC50=1.5 μM) or Ba/F3-MPLW515L cells (IC50=200 nM), but has considerably less activity against BCR-ABL harboring K562 cells (IC50=58 μM) and FLT3 mutation harboring MV4-11 cells (IC50=3 μM). Proliferation of parental Ba/F3 cells (Ba/F3-wt) stimulated with IL-3 is inhibited with an IC50 value of 1.4 μM.
- ATP-competitive inhibitor of JAK1/JAK2
- Selective for JAK1/JAK2 over JAK3
- Available in solid and solution forms
- Suitable for research use
Medchemexpress LLC Keratin sulfate | 169799-44-4 | 84.2% | 100 MG
Keratin sulfate is a heparin-related proteoglycan that interacts with receptors or alters their stability and function. It does not enhance the mitogenic effect of FGF-2.
- Off-white to light yellow solid appearance
- Insoluble in water at 40 mg/mL, requires ultrasonic for solubility
Medchemexpress LLC Vinblastine sulfate | 143-67-9 | 99.56% | 909.05 | 25 MG
Vinblastine sulfate is a cytotoxic alkaloid effective against various cancer types. It inhibits microtubule formation and suppresses nAChR with an IC50 of 8.9 μM. It blocks mitosis and induces apoptosis by altering p53 and causing DNA fragmentation, leading to an antiproliferative effect via Bax/Bcl-2 imbalance.
- Inhibits microtubule formation
- Suppresses nAChR activity
- Blocks mitosis and induces apoptosis
- Exhibits antiproliferative effects via Bax/Bcl-2 imbalance
- Modulates NFκB and JNK pathways
- Triggers apoptosis through mitochondrial pathway
- Targets Microtubule/Tubulin, Autophagy, and nAChR
- Involved in Cell Cycle/DNA Damage and Cytoskeleton pathways
- Soluble in water (50 mg/mL) and DMSO (≥ 44 mg/mL)
- Intended for research use only
Medchemexpress LLC Dermatan sulphate sodium | 54328-33-5 | 50 MG
Dermatan sulphate sodium | 54328-33-5 | 50 MG
Medchemexpress LLC Keratin sulfate | 169799-44-4 | 84.2% | 50 MG
Keratin sulfate is a heparin-related proteoglycan that interacts with the receptor or alters its stability and function. It does not enhance the mitogenic effect of FGF-2.
- Heparin-related proteoglycan
- Interacts with receptors or alters their stability and function
- Does not enhance the mitogenic effect of FGF-2
- For research use only
Medchemexpress LLC Dextran sulfate sodi 5g | 9011-18-1 | 35,000-45,000 Da | (C6H7Na3O14S3)n | 5 G
Dextran sulfate sodium salt (MW 35,000-45,000) is a highly sulfated polysaccharide provided as a powder for laboratory research applications, commonly used to induce experimental colitis in rodent models and to study complement, coagulation, and antiviral responses.
- High molecular weight fraction (35,000-45,000 Da) suitable for in vivo colitis models.
- Water-soluble sulfated polysaccharide with biological activity in complement and coagulation assays.
- Available in multiple laboratory pack sizes, including 5 g, for flexible experimental use.
- Supplied as a dry powder with recommended storage conditions to maintain stability.
- Applicable for in vitro and in vivo studies investigating inflammatory and antiviral mechanisms.
Medchemexpress LLC S-Methylisothiourea (sulfate) | 867-44-7 | 99.9% | C2H6N2S.1/2H2O4S | 1 ML
S-Methylisothiourea (sulfate) | 867-44-7 | 99.9% | C2H6N2S.1/2H2O4S | 1 ML
Medchemexpress LLC Polymyxin B Sulfate | 1405-20-5 | 96.88% | 500 MG
Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. It also acts as an antiendotoxin agent, showing endotoxin-neutralizing properties that can be used in adjunctive research for gram-negative sepsis. It demonstrates antibacterial activities in vitro and in vivo.
- Potent antibacterial agent
- Functions as an antiendotoxin agent
- Shows endotoxin-neutralizing properties
- Used in adjunctive research for gram-negative sepsis
- Demonstrates antibacterial activities both in vitro and in vivo
- Solid, white to off-white appearance
- Derived from microorganisms, Bacillus polymyxa
Medchemexpress LLC P-cresyl sulfate potassium (standard) | 91978-69-7 | 99.88% | 226.29 | 100 MG
P-cresyl sulfate potassium (standard) | 91978-69-7 | 99.88% | 226.29 | 100 MG